1 |
Técnicas
experimentales habituales en biología molecular |
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Intoducción y discusion general de las principales herramientas y métodos de la biología molecular |
Material preparado por la Dra. Adriana Geissinger |
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2 |
Estructura
del ADN |
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- Wu HM, Crothers DM. The locus of sequence-directed and protein-induced
DNA bending. Nature. 1984 308:509-513. |
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Koo HS, Wu HM, Crothers DM. DzNA
bending at adenine·thymine tracts. Nature.
1986 320:501-506. |
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3 |
Regulación de la transcripción en procariotas |
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Choy Hyon E., Seong Weon Park, Tsunehiro Aki, Pradip Parrack, Nobuyuki Fujita, Akira Ishihama and Sankar Adhya. Repression and activation of transcription by Gal and Lac repressors: involvement of alpha subunit of RNA polymerase. The EMBO Journal. 1995 14:4523-4529. |
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- Choy HE, Adhya S. Control of Gal transcription through DNA looping: inhibition of the initial transcribing complex. Proc Natl Acad Sci U S A. 1992 89:11264-11268 |
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4 |
Regulación de la transcripción en eucariotas |
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- Martin D, Orkin SH. Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf 1. Genes and Development 1990 4:1886-1898
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5 |
Regulación post transcripcional |
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- Carpousis AJ, Van Houwe G, Ehretsmann C, Krisch HM. Copurification
of E. coli RNAase E and PNPase: evidence for a specific association
between two enzymes important in RNA processing and degradation.
Cell. 1994 76:889-900.
- Paper Complementario: Annu.
Rev. Microbiol. 2007. 61:71–87 |
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6 |
Traducción |
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Barsanjit Mazumder, Prabha Sampath, Vasudevan Seshadri, Ratan K. Maitra,
Paul E. DiCorleto, and Paul L. Fox. Regulated Release of L13a from
the 60S Ribosomal Subunit as A Mechanism of Transcript-Specific Translational
Control. Cell. 2003 115:187–198
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Material de apoyo doble hibrido ··> |
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7 |
Genómica
funcional |
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Victoria Brown, Peng Jin, Stephanie Ceman,Jennifer C. Darnell, William
T. O’Donnell, Scott A. Tenenbaum, Xiaokui Jin, Yue Feng, Keith
D. Wilkinson,
Jack D. Keene, Robert B. Darnell, and Stephen T. Warren. Microarray
Identification of FMRP-Associated Brain mRNAs and Altered mRNA Translational
Profiles in Fragile X Syndrome. Cell. 2001 107:477–487 |
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CUESTIONARIO FINAL |
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